Is breast tomosynthesis recommended as an adjunct to population-based breast cancer screening mammography for women with dense breasts? Recommendation Consequently, the benefits of handheld ultrasound as an adjunct to population-based breast cancer screening mammography for women with dense breasts cannot outweigh the harm. In addition, the low specificity of the intervention group reflects its high recall rate in the J-START. However, breast cancer mortality rate reduction is the most important parameter that can be used to evaluate the efficacy of breast screening and no studies, including the J-START, have shown this. Also, there was a reduction in interval cancers. Furthermore, more small invasive cancers were detected in the intervention group than in the control group and were more frequently at stages 0 and 1. Preliminary results from the J-START show that sensitivity is significantly higher in the intervention group than in the control group, whereas the specificity is significantly lower. The results, therefore, can be generalized to women with dense breasts. ![]() The objective of the Japan Strategic Anti-Cancer Randomized Trial (J-START), which is the world’s first large-scale randomized controlled trial of supplemental ultrasound population-based breast screening, is to investigate the efficacy of adding ultrasound to screening mammography in 72,998 healthy Japanese women in their 40s. We advise against using handheld ultrasound as an adjunct to population-based breast cancer screening mammography for women with dense breasts. Is handheld ultrasound recommended as an adjunct to population-based breast cancer screening mammography for women with dense breasts? Recommendation
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